DMAE (dimethylaminoethanol) is naturally found in some fishes such as anchovies and sardines. DMAE is often given credit for having a mild stimulant effect without the quick up and down which comes from caffeine and other stimulants. It is also able to elevate mood and improve memory and learning. People who have taken DMAE for a period of a few weeks often report an increase in physical energy and less of a need for sleep. DMAE also increases the brain's production of acetylcholine.

DMAE is said to work by stepping up production of the neurotransmitter acetylcholine, a chemical in the brain required for proper mental functioning. Short-term memory, concentration, and learning capacity all depend on adequate levels of acetylcholine. DMAE shows a continual mild stimulation without side effects with DMAE as well as increased intelligence and physical energy.